Browsing by Author "Davidson, James"
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- ItemOpen AccessAn investigation of the role of N102 of the GnRH receptor in determining the potency of C-terminally modified agonist analogs(2000) Henshall-Howard, Marie-Paule Alix Emilie; Davidson, JamesThree GnRH receptors with the mutations N102A, N102D and N102K, which were derived from the human GnRH receptor by site directed mutagenesis, were expressed in COS-1 cells. The effects of these mutations on the potency of seven C-terminally modified GnRH agonist analogs for the stimulation of IP production were determined.