Browsing by Author "Andayi, Warren Andrew"
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- ItemOpen AccessSynthesis, antimalarial evaluation, Ç-hematin inhibition, and in silico and in vitro ADMET profiling of 4-aminoquinoline-hydroxypyridinone hybrids(2011) Andayi, Warren Andrew; Chibale, Kelly; Egan, Timothy JWith the aim of designing appropriate hybrid molecules as a strategy to fight drug resistant malaria parasites, 4-aminoquinoline-3,4-hydroxypyridinone hybrids were designed and synthesized. Their hypothesized mode of action was studied with respect to inhibition of hemozoin formation.