Gene mutations and expression in breast cancer

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dc.contributor.advisorParker, M Iqbalen_ZA
dc.contributor.authorDonninger, Howarden_ZA
dc.date.accessioned2014-07-28T14:54:49Z
dc.date.available2014-07-28T14:54:49Z
dc.date.issued2000en_ZA
dc.descriptionBibliography: leaves 163-190.
dc.description.abstractBreast cancer is the most common cause of death amongst women, with the incidence of the disease varying between countries. Like all other cancers, breast cancer is a multigenic disorder with mutations in oncogenes and tumour suppressor genes playing an important role in cellular transformation and ultimately in tumour formation. In this study, 40 breast cancer patients from the Western Cape province in South Africa and 4 breast cancer cell lines were screened for mutations in the human Ha-ras oncogene and the p53 tumour suppressor gene.en_ZA
dc.identifier.apacitationDonninger, H. (2000). <i>Gene mutations and expression in breast cancer</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Division of Medical Biochemistry. Retrieved from http://hdl.handle.net/11427/3124en_ZA
dc.identifier.chicagocitationDonninger, Howard. <i>"Gene mutations and expression in breast cancer."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Division of Medical Biochemistry, 2000. http://hdl.handle.net/11427/3124en_ZA
dc.identifier.citationDonninger, H. 2000. Gene mutations and expression in breast cancer. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Donninger, Howard AB - Breast cancer is the most common cause of death amongst women, with the incidence of the disease varying between countries. Like all other cancers, breast cancer is a multigenic disorder with mutations in oncogenes and tumour suppressor genes playing an important role in cellular transformation and ultimately in tumour formation. In this study, 40 breast cancer patients from the Western Cape province in South Africa and 4 breast cancer cell lines were screened for mutations in the human Ha-ras oncogene and the p53 tumour suppressor gene. DA - 2000 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2000 T1 - Gene mutations and expression in breast cancer TI - Gene mutations and expression in breast cancer UR - http://hdl.handle.net/11427/3124 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/3124
dc.identifier.vancouvercitationDonninger H. Gene mutations and expression in breast cancer. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Division of Medical Biochemistry, 2000 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/3124en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDivision of Medical Biochemistryen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherMedical Biochemistryen_ZA
dc.titleGene mutations and expression in breast canceren_ZA
dc.typeDoctoral Thesis
dc.type.qualificationlevelDoctoral
dc.type.qualificationnamePhDen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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