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Browsing Journal Articles by Subject "Obesity"

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Are women with history of pre-eclampsia starting a new pregnancy in good nutritional status in South Africa and Zimbabwe?

Author: Cormick, Gabriela ; Betrán, Ana P ; Harbron, Janetta ; Dannemann Purnat, Tina ; Parker, Catherine ; Hall, David ; Seuc, Armando H ; Roberts, James M ; Belizán, José M ; Hofmeyr, G J Date: 15 Jun 2018 Background Maternal nutritional status before and during pregnancy is an important contributor to pregnancy outcomes and early child health. The aim of this study was to describe the preconceptional nutritional status and ... Read more
Association between ethnicity and obesity with high-density lipoprotein (HDL) function and subclass distribution

Author: Woudberg, Nicholas J ; Goedecke, Julia H ; Blackhurst, Dee ; Frias, Miguel ; James, Richard ; Opie, Lionel H ; Lecour, Sandrine Date: 2016 Abstract Background Obesity and low high-density lipoprotein-cholesterol (HDL-C) levels are associated with cardiovascular risk. Surprisingly, despite a greater prevalence of obesity and lower HDL concentrations than white women, black South ... Read more
Association of serum leptin and adiponectin with anthropomorphic indices of obesity, blood lipids and insulin resistance in a Sub-Saharan African population

Author: Ayina, Clarisse Noël A ; Noubiap, Jean Jacques N ; Etoundi Ngoa, Laurent Serge ; Boudou, Philippe ; Gautier, Jean François ; Mengnjo, Michel Karngong ; Mbanya, Jean Claude ; Sobngwi, Eugène Date: 2016 Abstract Background There is little data on the metabolic effects of adipokines in sub-Saharan African populations. This study aimed to explore the potential relationship of leptin and adiponectin, with obesity, plasma lipids and insulin ... Read more
Blood pressure gradients and cardiovascular risk factors in urban and rural populations in Abia State South Eastern Nigeria using the WHO STEPwise approach

Author: Okpechi, Ikechi Gareth ; Chukwuonye, Innocent Ijezie ; Tiffin, Nicki ; Madukwe, Okechukwu Ojoemelam ; Onyeonoro, Ugochukwu Uchenna ; Umeizudike, Theophilus Ifeanyichukwu ; Ogah, Okechukwu Samuel Date: 2013 BACKGROUND: Developing countries of sub-Saharan Africa (SSA) face a double burden of non-communicable diseases (NCDs) and communicable diseases. As high blood pressure (BP) is a common global cardiovascular (CV) disorder associated with high ... Read more c b
Clinical features and outcomes of COVID-19 admissions in a population with a high prevalence of HIV and tuberculosis: a multicentre cohort study

Author: Parker, Arifa ; Boloko, Linda ; Moolla, Muhammad S ; Ebrahim, Nabilah ; Ayele, Birhanu T ; Broadhurst, Alistair G B ; Mashigo, Boitumelo ; Titus, Gideon ; de Wet, Timothy ; Boliter, Nicholas ; Rosslee, Michael-Jon ; Papavarnavas, Nectarios ; Abrahams, Riezaah ; Mendelson, Marc ; Dlamini, Sipho ; Taljaard, Jantjie J ; Prozesky, Hans W ; Mowlana, Abdurasiet ; Viljoen, Abraham J ; Schrueder, Neshaad ; Allwood, Brian W ; Lalla, Usha ; Dave, Joel A ; Calligaro, Greg ; Levin, Dion ; Maughan, Deborah ; Ntusi, Ntobeko A B ; Nyasulu, Peter S ; Meintjes, Graeme ; Koegelenberg, Coenraad F N ; Mnguni, Ayanda T ; Wasserman, Sean Date: 20 Jun 2022 Background There is still a paucity of evidence on the outcomes of coronavirus disease 2019 (COVID-19) among people living with human immunodeficiency virus (PWH) and those co-infected with tuberculosis (TB), particularly in ... Read more c b
Comparison of body fatness measurements by near-infrared reactance and dual-energy X-ray absorptiometry in normal-weight and obese black and white women

Author: Jennings, Courtney L ; Micklesfield, Lisa K ; Lambert, Mike I ; Lambert, Estelle V ; Collins, Malcolm ; Goedecke, Julia H Date: 2010 The aim of the present study was to compare body fat percent (BF %) using single-site near-IR reactance (NIR) and dual-energy X-ray absorptiometry (DXA) in a cohort of normal-weight (BMI < 25 kg/m2) black (n 102) and white (n 71); and obese ... Read more
Developing intervention strategies to optimise body composition in early childhood in South Africa

Author: Draper, Catherine E ; Tomaz, Simone A ; Stone, Matthew ; Hinkley, Trina ; Jones, Rachel A ; Louw, Johann ; Twine, Rhian ; Kahn, Kathleen ; Norris, Shane A Date: 2017 Purpose. The purpose of this research was to collect data to inform intervention strategies to optimise body composition in South African preschool children. Methods. Data were collected in urban and rural settings. Weight status, physical ... Read more
Differing patterns of overweight and obesity among black men and women in Cape Town: the CRIBSA study

Author: Peer, Nasheeta ; Lombard, Carl ; Steyn, Krisela ; Gwebushe, Nomonde ; Levitt, Naomi Date: 2014 Objectives To ascertain the prevalence and determinants of overweight/obesity in the 25-74-year-old urban black population of Cape Town and examine the changes between 1990 and 2008/09. METHODS: In 2008/09, a representative cross-sectional ... Read more c b
DNA methylation of FKBP5 in South African women: associations with obesity and insulin resistance

Author: Willmer, Tarryn ; Goedecke, Julia H ; Dias, Stephanie ; Louw, Johan ; Pheiffer, Carmen Date: 21 Sep 2020 Abstract Background Disruption of the hypothalamic–pituitary–adrenal (HPA) axis, a neuroendocrine system associated with the stress response, has been hypothesized to contribute to obesity ... Read more
Erratum to: Investigation of the association between the TCF7L2 rs7903146 (C/T) gene polymorphism and obesity in a Cameroonian population: a pilot study

Author: Nguimmo-Metsadjio, Aurelie ; Atogho-Tiedeu, Barbara ; Noubiap, Jean Jacques ; Evehe, Marie-Solange ; Djokam-Dadjeu, Rosine ; Donfack, Olivier Sontsa ; Nanfa, Dieudonne ; Mato, Edith Pascale M ; Ngwa, Elvis Ndonwi ; Guewo-Fokeng, Magellan ; Pokam-Fosso, Priscille ; Mbacham, Wilfred F ; Mbanya, Jean Claude ; Sobngwi, Eugène Date: 2017 OBJECTIVE: This study aimed at investigating the association between the rs7903146 (C/T) polymorphism of the TCF7L2 gene with obesity in a Cameroonian population. METHOD: This was a case-control pilot study including 61 obese and 61 non-obese ... Read more
Exercise intervention alters HDL subclass distribution and function in obese women

Author: Woudberg, Nicholas J ; Mendham, Amy E ; Katz, Arieh A ; Goedecke, Julia H ; Lecour, Sandrine Date: 10 Oct 2018 Background Obesity is associated with a change in high-density lipoprotein (HDL) function and subclass. Exercise training reduces cardiovascular risk in obese patients. We aimed to explore the effect of an exercise training ... Read more
Factors associated with excessive body fat in men and women: cross-sectional data from Black South Africans living in a rural community and an urban township

Author: Okop, Kufre Joseph ; Levitt, Naomi ; Puoane, Thandi Date: 2015 Objective To determine the factors associated with excessive body fat among black African men and women living in rural and urban communities of South Africa. METHODS: This is a cross-sectional analysis of data from the Prospective Urban and ... Read more c b
Fat Mass and Obesity-Associated (FTO) Gene Polymorphisms Are Associated with Physical Activity, Food Intake, Eating Behaviors, Psychological Health, and Modeled Change in Body Mass Index in Overweight/Obese Caucasian Adults

Author: Harbron, Janetta ; van der Merwe, Lize ; Zaahl, Monique ; Kotze, Maritha ; Senekal, Marjanne Date: 2014 The fat mass and obesity-associated (FTO) gene is currently recognized as the most robust predictor of polygenic obesity. We investigated associations between the FTO rs1421085 and rs17817449 polymorphisms and the FTO rs1421085–rs17817449 ... Read more
Four-year trends in adiposity and its association with hypertension in serial groups of young adult university students in urban Cameroon: a time-series study

Author: Choukem, Simeon-Pierre ; Kengne, André Pascal ; Nguefack, Maxime-Leolein ; Mboue-Djieka, Yannick ; Nebongo, Daniel ; Guimezap, Jackson T ; Mbanya, Jean Claude Date: 2017 Abstract Background Obesity is a major risk factor for non-communicable diseases (NCDs) and is growing rapidly globally including in sub-Saharan Africa (SSA). We aimed to assess the trend in adiposity markers in Cameroonian university students, ... Read more
Genetic variation at selected SNPs in the leptin gene and association of alleles with markers of kidney disease in a Xhosa population of South Africa

Author: Okpechi, Ikechi G ; Rayner, Brian L ; van der Merwe, Lize ; Mayosi, Bongani M ; Adeyemo, Adebowale ; Tiffin, Nicki ; Ramesar, Rajkumar Date: 2010 BACKGROUND: Chronic kidney disease (CKD) is a significant public health problem that leads to end-stage renal disease (ESRD) with as many as 2 million people predicted to need therapy worldwide by 2010. Obesity is a risk factor for CKD and ... Read more c b
Gut microbiota, short chain fatty acids, and obesity across the epidemiologic transition: the METS-Microbiome study protocol

Author: Dugas, Lara R ; Lie, Louise ; Plange-Rhule, Jacob ; Bedu-Addo, Kweku ; Bovet, Pascal ; Lambert, Estelle V ; Forrester, Terrence E ; Luke, Amy ; Gilbert, Jack A ; Layden, Brian T Date: 06 Aug 2018 Background While some of the variance observed in adiposity and weight change within populations can be accounted for by traditional risk factors, a new factor, the gut microbiota, has recently been associated with obesity. ... Read more
Health status of primary school educators in low socio-economic areas in South Africa

Author: Senekal, Marjanne ; Seme, Zibuyile ; de Villiers, Anniza ; Steyn, Nelia P Date: 25 Feb 2015 Background: Non-communicable Diseases (NCDs) are major health concerns in South Africa. According to the life cycle approach NCD prevention strategies should target children. Educators are important external factors influencing behaviour of ... Read more
Independent association of resting energy expenditure with blood pressure: confirmation in populations of the African diaspora

Author: Creber, Chloe ; Cooper, Richard S ; Plange-Rhule, Jacob ; Bovet, Pascal ; Lambert, Estelle V ; Forrester, Terrence E ; Schoeller, Dale ; Riesen, Walter ; Korte, Wolfgang ; Cao, Guichan ; Luke, Amy ; Dugas, Lara R Date: 10 Jan 2018 Background: Obesity is a major risk factor for hypertension, however, the physiologic mechanisms linking increased adiposity to elevations in blood pressure are not well described. An increase in resting energy expenditure (REE) is an obligatory ... Read more
Independent association of resting energy expenditure with blood pressure: confirmation in populations of the African diaspora

Author: Dugas, Lara R Date: 2018 Obesity is a major risk factor for hypertension, however, the physiologic mechanisms linking increased adiposity to elevations in blood pressure are not well described. An increase in resting energy expenditure (REE) is an obligatory consequence ... Read more
Intra-familial and ethnic effects on attitudinal and perceptual body image: a cohort of South African mother-daughter dyads

Author: Mchiza, Zandile ; Goedecke, Julia ; Lambert, Estelle Date: 2011 BACKGROUND: International studies suggest ethnic differences in obesity prevalence may be due, in part, to differences in body image and body size dissatisfaction between groups. Further, there is evidence to suggest that there is a familial ... Read more c b

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