Browsing Journal Articles by Subject "Gag"

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Chimaeric HIV-1 subtype C Gag molecules with large in-frame C-terminal polypeptide fusions form virus-like particles.

Author: Halsey, Richard J ; Tanzer, Fiona L ; Meyers, Ann ; Pillay, Sirika ; Lynch, Alisson ; Shephard, Enid ; Williamson, Anna-Lise ; Rybicki, Edward P Date: 2008 HIV-1 Pr55 Gag virus-like particles (VLPs) are strong immunogens with potential as candidate HIV vaccines. VLP immunogenicity can be broadened by making chimaeric Gag molecules: however, VLPs incorporating polypeptides longer than 200 aa fused ... Read more
HIV type 1 subtype C gag and nef diversity in Southern Africa.

Author: Bredell, Helba ; Martin, Darren P ; Van Harmelen Joanne ; Varsani, Arvind ; Sheppard, Haynes W ; Donovan, R ; Gray, C ; HIVNET028 Study Team ; Williamson, C Date: 2007 Several HIV-1 subtype C-specific gag- and/or nef-based vaccines are currently intended for clinical trial in southern Africa. Here we provide sequences of 64 gag and 45 nef genes sampled in Malawi, Zambia, Zimbabwe, and South Africa and assess ... Read more
The PTAP sequence duplication in HIV-1 subtype C Gag p6 in drug-naive subjects of India and South Africa

Author: Sharma, Shilpee ; Aralaguppe, Shambhu G ; Abrahams, Melissa-Rose ; Williamson, Carolyn ; Gray, Clive ; Balakrishnan, Pachamuthu ; Saravanan, Shanmugam ; Murugavel, Kailapuri G ; Solomon, Suniti ; Ranga, Udaykumar Date: 2017 Abstract Background HIV-1 subtype C demonstrates several biological properties distinct from other viral subtypes. One such variation is the duplication of PTAP motif in p6 Gag. PTAP motif is a key player in viral budding. Here, we studied ... Read more

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Browsing Journal Articles by Subject "Gag"

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