Do proton pump inhibitors reduce the incidence of pharyngocutaneous fistulae following total laryngectomy?

Master Thesis

2013

Permanent link to this Item
http://hdl.handle.net/11427/2904
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thesis_hsf_2013_stephenson_ka (1).pdf (5.3 MB)
Authors
Stephenson, Katherine Anna
Supervisors
Fagan, Johan
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University of Cape Town

Department
Division of Otorhinolaryngology
Faculty
Faculty of Health Sciences
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Abstract
Pharyngocutaneous fistula is a common complication of total laryngectomy. We hypothesised that perioperative proton pump inhibitor (PPI) treatment could reduce the incidence of pharyngocutaneous fistulae. This prospective placebo-controlled double-blind randomised controlled trial compared PPI treatment (14 days enteral omeprazole) with a placebo in patients undergoing primary total laryngectomy. The incidence of pharyngocutaneous fistula was recorded.
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Includes abstract.


Includes bibliographical references.

Keywords
Otorhinolaryngology

Reference:

Stephenson, K. 2013. Do proton pump inhibitors reduce the incidence of pharyngocutaneous fistulae following total laryngectomy?. University of Cape Town.

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Masters