Preventing antimalarial resistance with artemisinin-based combination therapy
Journal Article
2004
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South African Journal for Continuing Medical Education
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University of Cape Town
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Abstract
Malaria morbidity and mortality is rising, principally as a result of increasing antimalarial resistance. Resistance means that there is a shift to the right in the dose-response (concentration effect) relationship. Plasmodium falciparum has developed clinically significant resistance to all classes of antimalarial drugs, with the possible exception of artemisinin derivatives.
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Reference:
Barnes, K. I. (2008). Preventing antimalarial resistance with artemisinin-based combination therapy. Continuing Medical Education, 22(4), 205.