• Perceptions of health-related quality of life among adults living with sickle cell disease in Cape Town, South Africa

  

   Authors: Ingram, Clair Date: 2018 Sickle cell disease (SCD) is a chronic, heritable blood disorder with affected individuals suffering from debilitating health issues and requiring frequent hospitalisation. SCD is highly prevalent in areas of the world where malaria is endemic ... Read more

• Genomics of Lynch syndrome and Constitutional mismatch repair deficiency syndrome

  

   Authors: Lamola, Lindiwe Date: 2018 Introduction: The mismatch repair system plays an important role in maintaining the genome integrity as it functions to correct mismatches during DNA replication. Heterozygous mutations in one of the mismatch repair (MMR) genes e.g. MLH1, ... Read more

• The genetics of anthracycline-induced cardiotoxicity in cancer patients

  

   Authors: Naidoo, Horacia Date: 2018 INTRODUCTION: Breast cancer makes up 25% of all cancers diagnosed worldwide. Despite an increasing yearly incidence, there has been a significant decrease in mortality owing to early diagnosis and advances in treatment. Anthracycline-based ... Read more

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