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Browsing by Author "Stutz, Helen"

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Isolation and characterization of n-alkane utilizing bacteria, which produce biomulsifiers

Author: Ghilamicael, Amanuel Menghs Date: 2003 Bacterial strains were isolated by enrichment cultures from oil-contaminated soil samples. In the present study, several strains, capable of growing on crude oil, were isolated. Isolates were screened for their inherent abilities to produce ... Read more
Priming with a recombinant pantothenate auxotroph of Mycobacterium bovis BCG and boosting with MVA elicits HIV-1 Gag specific CD8+ T cells

Author: Chapman, Rosamund ; Shephard, Enid ; Stutz, Helen ; Douglass, Nicola ; Sambandamurthy, Vasan ; Garcia, Irene ; Ryffel, Bernhard ; Jacobs, William ; Williamson, Anna-Lise Date: 2012 A safe and effective HIV vaccine is required to significantly reduce the number of people becoming infected with HIV each year. In this study wild type Mycobacterium bovis BCG Pasteur and an attenuated pantothenate auxotroph strain (BCGΔ panCD ... Read more c b
Priming with recombinant auxotrophic BCG expressing HIV-1 Gag, RT and Gp120 and boosting with recombinant MVA induces a robust T cell response in mice

Author: Chapman, Rosamund ; Stutz, Helen ; Jr, William Jacobs ; Shephard, Enid ; Williamson, Anna-Lise Date: 2013 In previous studies we have shown that a pantothenate auxotroph of Myocbacterium bovis BCG (BCGΔ panCD ) expressing HIV-1 subtype C Gag induced Gag-specific immune responses in mice and Chacma baboons after prime-boost immunization in combination ... Read more c b
The use of directed evolution to create a stable and immunogenic recombinant BCG expressing a modified HIV-1 Gag antigen

Author: Chapman, Rosamund ; Bourn, William R ; Shephard, Enid ; Stutz, Helen ; Douglass, Nicola ; Mgwebi, Thandi ; Meyers, Ann ; Chin'ombe, Nyasha ; Williamson, Anna-Lise Date: 2014 Numerous features make Mycobacterium bovis BCG an attractive vaccine vector for HIV. It has a good safety profile, it elicits long-lasting cellular immune responses and in addition manufacturing costs are affordable. Despite these advantages ... Read more c b

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Browsing by Author "Stutz, Helen"

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