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Browsing by Author "Sliwa, Karen"

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Association between exercise frequency with renal and cardiovascular outcomes in diabetic and non-diabetic individuals at high cardiovascular risk

Author: Böhm, Michael ; Schumacher, Helmut ; Werner, Christian ; Teo, Koon K ; Lonn, Eva M ; Mahfoud, Felix ; Speer, Thimoteus ; Mancia, Giuseppe ; Redon, Josep ; Schmieder, Roland E ; Sliwa, Karen ; Marx, Nikolaus ; Weber, Michael A ; Laufs, Ulrich ; Williams, Bryan ; Yusuf, Salim ; Mann, Johannes F E Date: 20 Jan 2022 Background: Guidelines recommend physical activity to reduce cardiovascular (CV) events. The association between physical activity and progression of chronic kidney disease (CKD) with and without diabetes is unknown. We assessed the association ... Read more
Biomarkers of ventricular remodelling in African hypertensives.

Author: Dike, Ojji Date: 2013 There is substantial evidence that the burden of hypertension, hypertension with left ventricular hypertrophy and hypertensive heart failure is very enormous in sub-Saharan Africa. There is therefore the need to look for easier and faster ... Read more
Characterisation of cardiac remodeling associated with pregnancy: providing insights to peripartum cardiomyopathy

Author: Kodogo, Vitaris Date: 2021 Introduction: Maternal cardiovascular changes that occur in pregnant women are usually well tolerated by most women experiencing an uncomplicated pregnancy and are reversable postpartum. However, pregnancy can induce adverse cardiac events ... Read more
Characteristics and outcomes of acute heart failure in sub Saharan Africa

Author: Sani, Mahmoud Umar Date: 2016 The main objective of this thesis was to study the clinical characteristics and short-term (6 months) outcome of acute heart failure as well as determine the role of conventional biomarker BNP and the novel biomarker Gal3 in the prognostication ... Read more
Detecting subclinical anthracycline therapy related cardiac dysfunction in low income country (SATRACD study)

Author: Zhang, Wanzhu Date: 2022 Introduction: Anthracycline therapy-related cardiac dysfunction (ATRCD) is the most common chemotherapy-induced cardiovascular toxicity. It begins with subclinical myocardial cell injury that can be detected using speckle tracking echocardiography ... Read more
Economic burden of heart failure: investigating outpatient and inpatient costs in abeokuta, southwest Nigeria

Author: Ogah, Okechukwu S ; Stewart, Simon ; Onwujekwe, Obinna E ; Falase, Ayodele O ; Adebayo, Saheed O ; Olunuga, Taiwo ; Sliwa, Karen Date: 2014 Background: Heart failure (HF) is a deadly, disabling and often costly syndrome world-wide. Unfortunately, there is a paucity of data describing its economic impact in sub Saharan Africa; a region in which the number of relatively younger ... Read more c b
Genetics of Peripartum Cardiomyopathy: Current Knowledge, Future Directions and Clinical Implications

Author: Spracklen, Timothy F ; Chakafana, Graham ; Schwartz, Peter J ; Kotta, Maria-Christina ; Shaboodien, Gasnat ; Ntusi, Ntobeko A B ; Sliwa, Karen Date: 15 Jan 2021 Peripartum cardiomyopathy (PPCM) is a condition in which heart failure and systolic dysfunction occur late in pregnancy or within months following delivery. Over the last decade, genetic advances in heritable cardiomyopathy have provided ... Read more c b
Haemorrhage and Other Complications in Pregnant Women on Anticoagulation for Mechanical Heart Valves; a Prospective Observational Cohort Study

Author: Kariv, Sarah Date: 2019 Objective: To document maternal and foetal morbidity and mortality in anticoagulated, pregnant patients with mechanical heart valves until 42 days postpartum. Methods: In a tertiary single-centre, prospective cohort, 178 consecutive patients ... Read more
Is there an association between sleeping patterns and other environmental factors with obesity and blood pressure in an urban African population?

Author: Pretorius, Sandra ; Stewart, Simon ; Carrington, Melinda J ; Lamont, Kim ; Sliwa, Karen ; Crowther, Nigel J Date: 2015 Beyond changing dietary patterns, there is a paucity of data to fully explain the high prevalence of obesity and hypertension in urban African populations. The aim of this study was to determine whether other environmental factors (including ... Read more c b
Maternal and fetal outcome of subsequent pregnancy in patients with documented peripartum cardiomyopathy

Author: Masuku, David Sifiso Date: 2018 AIM: Subsequent pregnancies (SSPs) in patients with peripartum cardiomyopathy (PPCM) have a high risk of heart failure relapse. We report on outcome of SSPs in PPCM patients in South Africa. METHODS AND RESULTS: Of the 18 PPCM patients with ... Read more
Mortality in patients treated for tuberculous pericarditis in sub-Saharan Africa.

Author: Mayosi, Bongani M ; Wiysonge, Charles Shey ; Ntsekhe, Mpiko ; Gumedze, Freedom ; Volmink Jimmy A ; Maartens, Gary ; Aje, Akinyemi ; Thomas, Baby M ; Thomas, Kandathil M ; Awotedu, Abolade A ; Bongani, Thembela ; Mntla, Phindile ; Maritz, Frans ; Blackett, Kathleen Ngu ; Nkouonlack, Duquesne C ; Burch, Vanessa C ; Rebe, Kevin ; Parrish, Andy ; Sliwa, Karen ; Vezi, Brian Z ; Alam, Nowshad ; Brown, Basil G ; Gould, Trevor ; Visser, Tim ; Magula, Nombulelo P ; Commerford, Patrick J Date: 2008 Tuberculous pericarditis is one of the most severe forms of extrapulmonary tuberculosis, causing death or disability in a substantial proportion of affected people.1,2 In Africa, the incidence of tuberculous pericarditis is rising as a result ... Read more
Occupational Post-Exposure Prophylaxis (PEP) against Human Immunodeficiency Virus (HIV) Infection in a Health District in Cameroon: Assessment of the Knowledge and Practices of Nurses

Author: Aminde, Leopold Ndemnge ; Takah, Noah Fongwen ; Dzudie, Anastase ; Bonko, Neville Mengnjo ; Awungafac, George ; Teno, Divine ; Mbuagbaw, Lawrence ; Sliwa, Karen Date: 2015 BACKGROUND: Health care providers are at risk of acquiring human immunodeficiency virus (HIV) infection from occupational exposure, with nurses being the most vulnerable. There is no data on the awareness of post-exposure prophylaxis (PEP) ... Read more c b
Pregnancy-associated heart failure: a comparison of clinical presentation and outcome between hypertensive heart failure of pregnancy and idiopathic peripartum cardiomyopathy

Author: Ntusi, Ntobeko B A ; Badri, Motasim ; Gumedze, Freedom ; Sliwa, Karen ; Mayosi, Bongani M Date: 2015 AIMS: There is controversy regarding the inclusion of patients with hypertension among cases of peripartum cardiomyopathy (PPCM), as the practice has contributed significantly to the discrepancy in reported characteristics of PPCM. We sought ... Read more c b
The role of melatonin in peripartum cardiomyopathy

Author: Nicholson, Lauren Date: 2013 Peripartum cardiomyopathy (PPCM) is a heart disease of unknown aetiology emerging in previously healthy women towards the end of pregnancy or first postpartum months. Previous studies have suggested that oxidative stress contributes to the ... Read more
Targeting heart rate as a novel therapeutic approach in acute heart failure

Author: Imamdin, Aqeela Date: 2018 Background and hypothesis: Standard pharmacological treatment for heart failure improves cardiac remodelling and survival in the setting of chronic heart failure, but is suboptimal in cases of acute heart failure (AHF). Peripartum cardiomyopathy ... Read more
The role and essence of pilot trials and subgroup analysis in cardiovascular research: the IMPI trial experience

Author: Isiguzo, Godsent Chichebem Date: 2019 Background Randomised control trials (RCTs) are capital-intensive projects and demand substantial human and capital resources. Therefore, proper planning, precise research questions and adequate thoughts are required in areas such as ... Read more

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Browsing by Author "Sliwa, Karen"

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