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Browsing by Author "Seedat, Soraya"

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Assessing post-traumatic stress disorder in South African adolescents: using the child and adolescent trauma survey (CATS) as a screening tool

Author: Suliman, S ; Kaminer, D ; Seedat, Soraya ; Stein, Dan J Date: 2005 BACKGROUND:Several studies have demonstrated that South African children and adolescents are exposed to high levels of violent trauma with a significant proportion developing PTSD, however, limited resources make it difficult to accurately ... Read more c b
The association between hypertension and depression and anxiety disorders: results from a nationally-representative sample of South African adults

Author: Grimsrud, Anna ; Stein, Dan J ; Seedat, Soraya ; Williams, David ; Myer, Landon Date: 2009 Objective: Growing evidence suggests high levels of comorbidity between hypertension and mental illness but there are few data from low- and middle-income countries. We examined the association between hypertension and depression and anxiety ... Read more c b
DSM-IV-defined common mental disorders:association with HIV testing, HIV-related fears, perceived risk and preventive behaviours among South African adults

Author: Myer, Landon ; Stein, Dan J ; Grimsrud, Anna T ; Herman, Allen ; Seedat, Soraya ; Moomal, Hashim ; Williams, David R Date: 2009 Background. There are few reports from South Africa on how common mental disorders may be associated with HIVrelated perceptions and behaviours. Methods. Between 2002 and 2004, 4 351 South African adults were interviewed. Psychiatric diagnoses ... Read more
Escitalopram in the prevention of posttraumatic stress disorder: a pilot randomized controlled trial

Author: Suliman, Sharain ; Seedat, Soraya ; Pingo, Janine ; Sutherland, Taryn ; Zohar, Joseph ; Stein, Dan J Date: 19 Feb 2015 Background: A small literature suggests that pharmacotherapy may be useful in the prophylaxis of posttraumatic stress disorder in patients presenting with major trauma. There is relatively little data, however, on the use of selective serotonin ... Read more c b
Impact of childhood trauma on functionality and quality of life in HIV-infected women

Author: Troeman, Zyrhea ; Spies, Georgina ; Cherner, Mariana ; Archibald, Sarah ; Fennema-Notestine, Christine ; Theilmann, Rebecca ; Spottiswoode, Bruce ; Stein, Dan ; Seedat, Soraya Date: 2011 BACKGROUND:While there are many published studies on HIV and functional limitations, there are few in the context of early abuse and its impact on functionality and Quality of Life (QoL) in HIV. METHODS: The present study focused on HIV in ... Read more c b
Impact of common mental disorders during childhood and adolescence on secondary school completion

Author: Myer, Landon ; Stein, Dan J ; Jackson, Pamela B ; Herman, Allen A ; Seedat, Soraya ; Williams, David R Date: 2009 There are few data from South Africa and other low- and middle-income countries on how mental disorders in childhood and adolescence may influence different aspects of socio-economic position, including educational attainment. We examined the ... Read more
The impact of voluntary exercise on relative telomere length in a rat model of developmental stress

Author: Botha, Martmari ; Grace, Laurian ; Bugarith, Kishor ; Russell, Vivienne ; Kidd, Martin ; Seedat, Soraya ; Hemmings, Sian Date: 2012 BACKGROUND: Exposure to early adverse events can result in the development of later psychopathology, and is often associated with cognitive impairment. This may be due to accelerated cell aging, which can be catalogued by attritioned telomeres. ... Read more c b
Life stress and mental disorders in the South African stress and health study

Author: Seedat, Soraya ; Stein, Dan J ; Jackson, Pamela B ; Heeringa, Steven G ; Williams, David R ; Myer, Landon Date: 2009 Background. Although stressful life events (SLEs) are associated with psychopathology, the contribution from distal and proximal events and the specificity of their association with common mental disorders require further exploration. We ... Read more
Mental health service use among South Africans for mood, anxiety and substance use disorders

Author: Seedat, Soraya ; Williams, David R ; Herman, Allen A ; Moomal, Hashim ; Williams, Stacey L ; Jackson, Pamela B ; Myer, Landon ; Stein, Dan J Date: 2009 Background. Europe and North America have low rates of mental health service use despite high rates of mental disorder. Little is known about mental health service use among South Africans. Design. A nationally representative survey of 4 351 ... Read more
Patterns of substance use in South Africa: results from the South African Stress and Health study

Author: Van Heerden, Margaretha S ; Grimsrud, Anna T ; Seedat, Soraya ; Myer, Landon ; Williams, David R ; Stein, Dan J Date: 2009 Background. There are limited data on substance use in South Africa. We describe patterns of substance use based on recent, nationally representative data. Methods. Data were derived from the 2002 - 2004 South African Stress and Health (SASH) ... Read more
Perceived discrimination and mental health disorders: the South African Stress and Health study

Author: Moomal, Hashim ; Jackson, Pamela B ; Stein, Dan J ; Herman, Allen ; Myer, Landon ; Seedat, Soraya ; Madela-Mntla, Edith ; Williams, D R Date: 2009 Objectives. To describe the demographic correlates of perceived discrimination and explore the association between perceived discrimination and psychiatric disorders. Design. A national household survey was conducted between 2002 and 2004 ... Read more
Pharmacotherapy for post-traumatic stress disorder - a systematic review and meta-analysis

Author: Ipser, Jonathan ; Seedat, Soraya ; Stein, Dan J Date: 2006 Background. Post-traumatic stress disorder (PTSD) is a prevalent and disabling condition. Evidence that PTSD is characterised by specific psychobiological dysfunctions has contributed to a growing interest in use of medication in its treatment. ... Read more
Pharmacotherapy for post-traumatic stress disorder- a systematic review and meta-analysis

Author: Ipser, Jonathan ; Seedat, Soraya ; Stein, Dan J Date: 2006 Background. Post-traumatic stress disorder (PTSD) is a prevalent and disabling condition. Evidence that PTSD is characterised by specific psychobiological dysfunctions has contributed to a growing interest in use of medication in its treatment. ... Read more
Socio-behaviour challenges to phase III HIV vaccine trials in sub-Saharan Africa

Author: Smit, Joalida ; Middelkoop, Keren ; Myer, Landon ; Lindegger, Graham ; Swartz, Leslie ; Seedat, Soraya ; Tucker, Tim ; Wood, Robin ; Bekker, Linda-Gail ; Stein, Dan J Date: 2005 Background: A number of countries in sub-Saharan Africa are preparing for HIV vaccine efficacy trials. Social and behavioural factors related to HIV transmission require examination in each setting where these trials are considered. As part ... Read more
The prevalence and correlates of hallucinations in a general population sample: findings from the South African Stress and Health Study

Author: Temmingh, H S ; Stein, Dan J ; Seedat, Soraya ; Williams, D R Date: 2011 Objective: Large epidemiological surveys conducted in the developed world have found rates of psychotic symptoms in the general population to be as high as 10-28%. However, there are few data available from developing countries, including ... Read more
The South African Stress and Health (SASH) study: 12-month and lifetime prevalence of common mental disorders

Author: Herman, Allen A ; Stein, Dan J ; Seedat, Soraya ; Heeringa, Steven G ; Moomal, Hashim ; Williams, David R Date: 2009 Background. The South African Stress and Health (SASH) study is the first large-scale population-based study of common mental disorders in the country. This paper provides data on the 12-month and lifetime prevalence of these conditions. ... Read more
Understanding the impact of hazardous and harmful use of alcohol and/or other drugs on ARV adherence and disease progression

Author: Kader, Rehana ; Govender, Rajen ; Seedat, Soraya ; Koch, John Randy ; Parry, Charles Date: 2015 The objective of this study was to understand the impact of hazardous and harmful use of alcohol and/or other drugs on ARV adherence and disease progression among HIV patients. A cross-sectional study design was used. A total of 1503 patients ... Read more c b

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