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Browsing by Author "Muchohi, Simon"

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A phase I trial to evaluate the safety and pharmacokinetics of low-dose methotrexate as an anti-malarial drug in Kenyan adult healthy volunteers

Author: Chilengi, Roma ; Juma, Rashid ; Abdallah, Ahmed ; Bashraheil, Mahfudh ; Lodenyo, Hudson ; Nyakundi, Priscilla ; Anabwani, Evelyn ; Salim, Amina ; Mwambingu, Gabriel ; Wenwa, Ednah ; Jemutai, Julie ; Kipkeu, Chemtai ; Oyoo, George ; Muchohi, Simon ; Kokwaro, Gilber Date: 2011 BACKGROUND: Previous investigations indicate that methotrexate, an old anticancer drug, could be used at low doses to treat malaria. A phase I evaluation was conducted to assess the safety and pharmacokinetic profile of this drug in healthy ... Read more c b

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