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Browsing by Author "Mehta, Ushma"

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Effect of artemether-lumefantrine policy and improved vector control on malaria burden in KwaZulu-Natal, South Africa

Author: Barnes, Karen I ; Durrheim, David N ; Little, Francesca ; Jackson, Amanda ; Mehta, Ushma ; Allen, Elizabeth ; Dlamini, Sicelo S ; Tsoka, Joyce ; Bredekamp, Barry ; Mthembu, D Jotham ; White, Nicholas J ; Sharp, Brian L Date: 2005 Between 1995 and 2000, KwaZulu–Natal province, South Africa, experienced a marked increase in Plasmodium falciparum malaria, fuelled by pyrethroid and sulfadoxine-pyrimethamine resistance. In response, vector control was strengthened and ... Read more
Effect of artemether-lumefantrine policy and improved vector control on malaria burden in KwaZulu-Natal, South Africa

Author: Barnes, Karen I ; Durrheim, David N ; Little, Francesca ; Jackson, Amanda ; Mehta, Ushma ; Allen, Elizabeth ; Dlamini, Sicelo S ; Tsoka, Joyce ; Bredenkamp, Barry ; Mthembu, D Jotham Date: 2005 In KwaZulu-Natal strengthening of vector control and a change in antimalarial treatment policy to use of artemether-lumefantrine has been associated with a decrease in malaria cases, admissions, and deaths. Read more c b
Eliciting harms data from trial participants: how perceptions of illness and treatment mediate recognition of relevant information to report

Author: Allen, Elizabeth ; Barnes, Karen ; Mushi, Adiel ; Massawe, Isolide ; Staedke, Sarah ; Mehta, Ushma ; Vestergaard, Lasse ; Lemnge, Martha ; Chandler, Clare Date: 2011 Background: There is no consensus on the ideal methodology for eliciting participant-reported harms, but question methods influence the extent and nature of data detected. This gives potential for measurement error and undermines meta-analyses ... Read more c b
Evaluating harm associated with anti-malarial drugs: a survey of methods used by clinical researchers to elicit, assess and record participant-reported adverse events and related data

Author: Allen, Elizabeth ; Chandler, Clare ; Mandimika, Nyaradzo ; Pace, Cheryl ; Mehta, Ushma ; Barnes, Karen Date: 2013 BACKGROUND:Participant reports of medical histories, adverse events (AE) and non-study drugs are integral to evaluating harm in clinical research. However, interpreting or synthesizing results is complicated if studies use different methods ... Read more c b
How experiences become data: the process of eliciting adverse event, medical history and concomitant medication reports in antimalarial and antiretroviral interaction trials

Author: Allen, Elizabeth ; Mushi, Adiel ; Massawe, Isolide ; Vestergaard, Lasse ; Lemnge, Martha ; Staedke, Sarah ; Mehta, Ushma ; Barnes, Karen ; Chandler, Clare Date: 2013 BACKGROUND:Accurately characterizing a drug's safety profile is essential. Trial harm and tolerability assessments rely, in part, on participants' reports of medical histories, adverse events (AEs), and concomitant medications. Optimal methods ... Read more c b
Influences on participant reporting in the World Health Organisation drugs exposure pregnancy registry; a qualitative study

Author: Allen, Elizabeth N ; Gomes, Melba ; Yevoo, Lucy ; Egesah, Omar ; Clerk, Christine ; Byamugisha, Josaphat ; Mbonye, Anthony ; Were, Edwin ; Mehta, Ushma ; Atuyambe, Lynn M Date: 31 Oct 2014 Background: The World Health Organisation has designed a pregnancy registry to investigate the effect of maternal drug use on pregnancy outcomes in resource-limited settings. In this sentinel surveillance system, detailed health and drug use ... Read more c b
Protocol for a drugs exposure pregnancy registry for implementation in resource-limited settings

Author: Mehta, Ushma ; Clerk, Christine ; Allen, Elizabeth ; Yore, Mackensie ; Sevene, Esperanca ; Singlovic, Jan ; Petzold, Max ; Mangiaterra, Viviana ; Elefant, Elizabeth ; Sullivan, Frank ; Holmes, Lewis ; Gomes, Melba Date: 2012 BACKGROUND: The absence of robust evidence of safety of medicines in pregnancy, particularly those for major diseases provided by public health programmes in developing countries, has resulted in cautious recommendations on their use. We ... Read more c b

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Browsing by Author "Mehta, Ushma"

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