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Browsing by Author "Hardie, Diana"

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A Molecular Epidemiological Study of Human Parainfluenza 4 in the Western Cape, South Africa

Author: Parsons, Jane Date: 2021 Background Human parainfluenza 4 (HPIV 4) is a recognised cause of acute respiratory infection (ARI). However, there is no published data on the epidemiology of this virus in South Africa. This thesis describes the molecular epidemiology of ... Read more
Cytomegalovirus viraemia in immunocompromised children in Cape Town

Author: Hsiao, Nei-Yuan Date: 2009 Includes bibliographical references (leaves 54-62). Read more
Evaluation of two SARS-CoV-2 immunoassays

Author: Naidoo, Michelle Date: 2022 Aim: The purpose of this study is to verify the performance of the Roche Elecsys ® antinucleocapsid (qualitative) and anti-spike (quantitative) SARS-CoV-2 immunoassays to determine whether the performance of the assays is acceptable for ... Read more
The failure of routine rapid HIV testing: a case study of improving low sensitivity in the field

Author: Wolpaw, Benjamin ; Mathews, Catherine ; Chopra, Mickey ; Hardie, Diana ; de Azevedo, Virginia ; Jennings, Karen ; Lurie, Mark Date: 2010 BACKGROUND:The rapid HIV antibody test is the diagnostic tool of choice in low and middle-income countries. Previous evidence suggests that rapid HIV diagnostic tests may underperform in the field, failing to detect a substantial number of ... Read more c b
Hepatitis A seroprevalence in South Africa: Are we in epidemiological transition?

Author: Enoch, Annabel Date: 2018 Hepatitis A virus (HAV) is the most common cause of viral hepatitis worldwide. Infection with HAV is vaccine preventable, however, a vaccine against HAV is not included in the Expanded Programme on Immunization in South Africa (SA). South ... Read more
Molecular characterisation of virus in the brains of patients with measles inclusion body encephalitis (MIBE)

Author: Hardie, Diana ; Albertyn, Christine ; Heckmann, Jeannine ; Smuts, Heidi Date: 2013 BACKGROUND: During 2009/10 a major measles epidemic caused by genotype B3 occurred in South Africa. Measles inclusion body encephalitis (MIBE) was diagnosed in a number of highly immuno-compromised HIV patients. The diagnosis was based on ... Read more c b
Patient experiences following acute HIV infection diagnosis and counseling in South Africa

Author: Wolpaw, Benjamin J ; Mathews, Catherine ; Mtshizana, Yolisa ; Chopra, Mickey ; Hardie, Diana ; Lurie, Mark N ; De Azevedo, Virginia ; Jennings, Karen Date: 2014 Individuals in the acute stage of HIV infection (AHI) have an elevated potential to transmit HIV and play a critical role in the growth of the epidemic. Routine identification and counseling of individuals during AHI could decrease transmission ... Read more c b
Silent casualties from the measles outbreak in South Africa

Author: Albertyn, Christine ; Van der Plas, Helen ; Hardie, Diana ; Candy, Sally ; Tomoka, Tamiwe ; LeePan, Edward B ; Heckmann, Edward B Date: 2011 South Africa, home to the world’s largest population of people living with HIV (5.7 million), experienced a measles outbreak that started in late 2009.1 There was a stepped increase in cases of measles, with the highest incidence reported in ... Read more
The implementation of a rapid sample preparation method for the detection of SARS-CoV-2 in a diagnostic laboratory in South Africa

Author: Marais, Gert J K Date: 2022 The SARS-CoV-2 pandemic has resulted in shortages of both critical reagents for nucleic acid purification and highly trained staff as supply chains are strained by high demand, public health measures and frequent quarantining and isolation ... Read more